尿嘧啶与肾上腺素相互作用的伏安特性及理论研究Cyclic Voltammetry Characteristic and Theoretical Study on the Interaction between Uracil and Adrenaline
裴玲,薛梅,郁章玉
摘要(Abstract)：
采用循环伏安法研究了尿嘧啶在pH=7.4的KRPB缓冲溶液中对肾上腺素电子转移性质的影响.实验结果表明,尿嘧啶对肾上腺素有一定的稳定作用,能在一定程度上抑制肾上腺素的氧化,使其氧化峰电位正移,峰电流减小,氧化反应能力降低.同时用密度泛函理论(DFT)的B3LYP方法,在6-31+G(d)基组水平上,对尿嘧啶与肾上腺素所能形成的5种1∶1复合物的结构进行了优化计算,并对各物种的能量进行零点振动能(ZPVE)和基组叠加误差(BSSE)校正.计算结果表明,尿嘧啶与肾上腺素存在氢键作用,从理论上解释了有关的实验现象.
关键词(KeyWords)： 尿嘧啶;肾上腺素;循环伏安;密度泛函理论;氢键
基金项目(Foundation): 山东省自然科学基金资助项目(Y2000B03);; 山东省教育厅科技计划重点项目(J04B11)
作者(Author): 裴玲,薛梅,郁章玉
DOI: 10.16393/j.cnki.37-1436/z.2006.05.019
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