氰戊菊酯对牙鲆鳃细胞系体外的细胞毒性In Vitro Cytotoxicity of the Pyrethroid Insecticide Fenvalerate to the Flounder (Paralichthys Olivaceus) Gill Cells
兰欣
摘要(Abstract):
采用牙鲆鳃细胞系FG-9307,测定拟除虫菊酯类农药氰戊菊酯的体外细胞毒性.细胞生长速度在测试质量浓度5,10和15μg/mL显著降低.此外,三种应用比较广泛的测试终点方法——中性红吸收实验法、四唑盐比色实验法、细胞蛋白分析法被用于检测氰戊菊酯的体外细胞毒性.实验证明三种测试方法的细胞毒性的相关性很高,并不因测试终点不同而不同.这说明FG细胞系有可能成为检测氰戊菊酯体外细胞毒性的合适的生物指标.
关键词(KeyWords): 氰戊菊酯;牙鲆鳃细胞系;体外细胞
基金项目(Foundation): 国家科技部863项目(2001AA649040)
作者(Author): 兰欣
DOI: 10.16393/j.cnki.37-1436/z.2010.05.009
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