曹科伟,张燕,秦梅,李霞,马心英,李金金,郁章玉

• 1:曲阜师范大学
• 2:菏泽学院

摘要(Abstract)：

在不同的酸度、起止电位、扫描圈数、扫描速度条件下,于一定浓度的苯丙氨酸聚合底液中制作玻碳修饰电极,利用浓度为2.2×10-5mol/L的肾上腺素作为探针进行伏安测定,比较产生响应电流的大小,探讨了聚L-苯丙氨酸的最佳聚合条件.结果表明:Na2HPO4-C6H8O7缓冲溶液pH为5.0,扫描电位区间为-0.8~3.0 V,聚合圈数为8圈,聚合扫速为120 mV/s条件下制得的修饰电极对肾上腺素产生最大响应电流,且该修饰电极因稳定性和重现性良好而具有较高的应用价值.

关键词(KeyWords)： L-苯丙氨酸;修饰电极;肾上腺素;循环伏安

Abstract:

Keywords:

基金项目(Foundation): 山东省自然科学基金资助项目(ZR2009MB003)

作者(Author): 曹科伟,张燕,秦梅,李霞,马心英,李金金,郁章玉

DOI: 10.16393/j.cnki.37-1436/z.2010.05.007

参考文献(References)：

• [1]郁章玉,吴树新,郭道军.玻碳电极的物理预处理方法[J].化学世界,2001,(1):6-9.
• [2]李小春,马心英,李霞,等.极化玻碳电极和聚L-半胱氨酸玻碳修饰电极稳定性的研究[J].菏泽学院学报,2009.31(5):91-94.
• [3]马心英.聚赖氨酸修饰电极在抗坏血酸共存时测定去甲肾上腺素[J].化学研究与应用,2008,20(8):980-983.
• [4]孙登明,胡文娜,马伟.聚L-精氨酸修饰电极的制备及对尿酸的测定[J].应用化学,2008,25(8):913-917.
• [5]Santos D P,Zanoni M V B,Bergamini M F,et al.Poly(glutamic acid)nanofibre modified glassy carbon elec-trode:Characterization by atomic force microscopy,voltam-metry and electrochemical impedance[J].Electrochim.Acta,2008,53:3991?4000.
• [6]Carlos A M H,Monica C L,Marco A Q.ElectrochemicalBehaviour of Dopamine at Covalent Modified Glassy CarbonElectrode with L-Cysteine:Preliminary Results[J].Ma-ter.Res.,2009,12(4):375-384.
• [7]Wang C Y,Wang Z X,Guan J,et al.Voltammetric Deter-mination of Meloxicam in Pharmaceutical Formulation andHuman Serum at Glassy Carbon Electrode Modified by Cys-teic Acid Formed by Electrochemical Oxidation of L-cys-teine[J].Sensors,2006,6:1139-1152.
• [8]Zhang L.Covalent modification of glassy carbon electrodewith cysteine for the determination of dopamine in the pres-ence of ascorbic acid[J].Microchim.Acta,2008,161:191?200.
• [9]李小春.聚L-ASP修饰电极对儿茶酚胺类物质的电分析作用[D].曲阜:曲阜师范大学,2010:8-9.
• [10]丁荣昌,董文举,冯九菊.尿酸在聚L 2苯丙氨酸修饰电极上的伏安测定[J].应用化学,2009,26(7):822-825.
• [11]江明性.药理学[M].第3版.北京:人民卫生出版社,1991:73-83.
• [12]Xue K-H,Liu J-M,Wei R-B,et al.Electrochemicalbehavior of adrenaline at the carbon atom wire modified e-lectrode[J].Chem.Phys.,2006,317:319-326.
• [13]Zhang H-M,Zhou X-L,Hui R-T,et al.Studies ofthe electrochemical behavior of epinephrine at a homocys-teine self-assembled electrode[J].Talanta,2002,56:1081-1088
• [14]Yu Z-Y,Kong D-S,Wu S-X,et al.Electrocatalysisof the SiC Particle-Modified Glassy Carbon Electrode forthe Oxidation of Adrenaline[J].J.Chin.Chem.Soc.,2004,51(6):1287-1292.
• [15]Yu Z-Y,Kong D-S,Wu S-X,et al.Electrocatalysisof Polished Glassy Carbon Electrode with Silicon CarbideAbrasive Paper for the Oxidation of Adrenaline[J].IndianJ.Chem.,2004,43A(11):2340-2342.
• [16]Yu Z-Y,Kong D-S,Wu S-X,Wang L,et al.Elec-trocatalysis of the SiC Particle-Modified Glassy Carbon E-lectrode for the Oxidation of Adrenaline in KRPB Physio-logical Solution[J].J.Serb.Chem.Soc.,2005,70(5):745-752.